Most NMDs are incurable, however exercise is known to improve quality of life, reduce degradation rate of muscle, improve movement, improve symptoms or co-morbidities of the disease, prolong independence and reduce risk of injuries.

Resistance training has been shown to improve motor function in this population. Resistance and aerobic training improves physical fitness, strength and functional performance and capacity. Regular flexibility training assists with reducing/preventing contractures in people with muscular dystrophy, spinal cord injury and stroke.

Exercise not only improves movement and muscle control but also physiology including improved cardiovascular and respiratory function, leading to increased longevity. Furthermore, exercise improves mental wellbeing with social interactions and a sense of accomplishment.